What is it and where does it come from?

Hordenine (C10H15NO) is a compound that is found in many grains, grassy plants, and in some species of hallucinogenic cactus. It is chemically related to the amino acid tyramine.

Hordenine is quickly gaining a reputation as an effective supplement that helps people lose weight. The research on hordenine and fat loss is minimal, but scientists hypothesize that hordenine helps people lose weight, in part, by stimulating norepinephrine release. This makes hordenine a central nervous system stimulant.

Norepinephrine - an excitatory hormone that energizes the body - is lipolytic; it liberates lipids from adipose tissue. When this occurs, liberated lipids are oxidized for energy - burned - and a reduction in overall body fat percentage should occur.

Once fatty acids are liberated, oxidized and body composition changed, hordenine is thought to realign the set point of the body. Set-point-theory (it's actually a hypothesis with evidence both for and against the concept) stipulates that the body prefers equilibrium and will resist changes in body mass. This process makes body composition change difficult and is one reason why losing body fat is difficult. By realigning the set-point to reflect the new body weight, hordenine helps you not only lose weight, but also keep it off for good.

Hordenine also helps with weight loss and healthy weight maintenance by slowing the digestion of food. This makes it easier to go longer between meals - lowering overall caloric intake, speeding satiation during feeding periods, and eliminating hunger pains and food cravings.

Hordenine is not an essential nutrient and no daily requirement (RDA) exists. No symptoms of deficiency exist.

All persons in good health can benefit from supplementing with hordenine.

Adhere to label directions.

Do use not use hordenine if you are taking other central nervous system stimulants (riphenidate, dextroamphetamine, nitroglycerine, pseudoephedrine and other stimulants), as hordenine is contraindicated and may result in anxiety, rapid heart beat, difficulty sleeping, headaches, nausea and dizziness.

Do not use hordenine if you are taking blood pressure medication, alpha blockers, beta blockers or asthma or allergy medications. Hordenine is contraindicated and may cause adverse effects.

Consult with a physician prior to using any nutritional supplement.